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临床试验/CTRI/2022/12/048541
CTRI/2022/12/048541尚未招募2/3 期

Randomised controlled clinical trial to compare the efficacy of madhuyukt sharpunkha choorna lep with betadine ointment in the management of dushta vrana.

Tilak Ayurved Mahavidyalaya, Pune1 个研究点 分布在 1 个国家目标入组 68 人开始时间: 2022年12月30日最近更新:
适应症

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
68
试验地点
1
主要终点
Darshan Paariksha- Akruti,Vrana strava,Vrana Tala,Vranagandha

研究概览

简要总结

Today wound is basic problem in surgical practice Surgeon deals with inflammation & problem in healing in any surgical disorder. Even though Vrana is a natural process of healing it should be protected from dosha dushti from various microorganism, which may affect the vrana and delay the normal healing process. Wound has different aspect for healing process If is left untreated can leads to complication. So we are looking for effective management. Dushta Vrana (Infected wound) is a common problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complicationsand maybecome fatal. Wound healingisanatural process, but factors like slough, infection and foreign bodies, affect the normal process of healing. A healthy wound in anormal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in the present concept, all efforts are directed to keep the wound clean during the various stages of its healing process. Wound is a physical injury to any of the tissues in the body that results in a break in the continuity of soft parts of body structures[8]. A process of healing of wound is a normal biological response to the injury that occurs naturally, as long as the local care is adequate. The normal phases of wound healing-reaction, regeneration, and remodeling take place without any difficulty, if wound is debrided properly of non-viable tissue and repaired it in a physiological manner. Acharya Sushruta has given much emphasis on Vaikruthapaham. Hence good wound healing with minimal or no scar formation is the prime motto.Sushruta, Charaka, Vaghbhata, Madhavakar and Sharangdhara have clearly mentioned that the Lakshanas of Dushta Vrana as foul smelling, continuously flowing pus discharge along with blood filled cavities, which can be correlated to non-healing or contaminated wound. Infected wounds mostly require surgical debridement to stabilize the patient as well as to promote healing process, longer hospitalization, and surgery with use of anaesthesia drug, wound care and also other expenses. MADHUYUKTA SHARPUNKHA CHOORNA LEP has property of non surgical debridement, less painful and economical. Hence it can be most affordable and convenient non surgical treatment.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Open Label

入排标准

年龄范围
10.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • •Patients having Dusta Vrana (infected Wound) irrespective of sex, age, occupation including surgical wounds 2) OPD & IPD patients from Shalya department of affiliated hospital 3) Dusta Vrana having dimension from 1 cm to 6 cm 4) Patients ready to give written consent will be selected. 5) Patients suffering from dushtavrana and lakshana like- Raga (redness).
  • •Utsannamamsa (pale granulation tissue).
  • •Vedanayukta(painful).
  • •Dustastrava(discharge).
  • •Dustagandhi(foul smelling).

排除标准

  • •Known case of -1) Osteomyelitis, Venous, Tubercular, Ischemic, Tropical, Neurogenic, malignant ulcers.2) Ulcers with gangrenous changes.
  • •Patient is suffering from HIV.
  • •Wound size more than 6 cm.
  • •Diabetic wound.

结局指标

主要结局

Darshan Paariksha- Akruti,Vrana strava,Vrana Tala,Vranagandha

时间窗: Baseline,1st, 3rd,5th,7th 10th Day

Saparshan pariksha-Sparshatva,local temperature

时间窗: Baseline,1st, 3rd,5th,7th 10th Day

Prashn Pariksha- Daha,Vedna, kandu

时间窗: Baseline,1st, 3rd,5th,7th 10th Day

次要结局

  • Recurrance of Akruti,Vrana strava,Vrana Tala,Vranagandha(,Sparshatva,local temperature,Daha,Vedna, kandu)

研究者

发起方
Tilak Ayurved Mahavidyalaya, Pune
申办方类型
Research institution and hospital

研究点 (1)

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