MedPath

Development of an Empowerment Intervention for Young Women Living With HIV

Phase 2
Completed
Conditions
HIV
Registration Number
NCT01454921
Lead Sponsor
University of North Carolina, Chapel Hill
Brief Summary

This study will develop/adapt a culturally appropriate secondary prevention intervention for young, Human Immunodeficiency Virus (HIV)-positive women through intervention groups, evaluate its acceptability and feasibility, make appropriate modifications, and manualize the intervention in preparation for a full-scale randomized trial.

Once the intervention is developed/adapted, the sites will pilot the interventions twice to enable modifications. The intervention aims to address the following concerns: 1) reducing the risk of young women infected with HIV transmitting the virus to their sexual partners, and 2) preventing young women infected with HIV from re-infection with a new viral strain or co-infection with another sexually transmitted disease (STD). Data will be collected to assess the feasibility and acceptability of the newly developed intervention using both quantitative and qualitative methods at each iteration.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
43
Inclusion Criteria
  • Female at birth and currently female;
  • Receives services at one of the selected ATN sites or their community partners
  • HIV-infected as documented by medical record review or verbal verification with referring professional
  • Between the ages of 16-24 years (inclusive) at the time of informed consent/assent
  • Ability to understand both written and spoken English
  • Gives informed consent/assent for study participation
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Exclusion Criteria
  • Presence of active, serious psychiatric symptoms (e.g., hallucinations, thought disorder) that would impair a participant's ability to meet the study requirements

  • Visibly distraught (e.g., suicidal, homicidal, exhibiting violent behavior)

  • Intoxicated or under the influence of alcohol or other substances at the time of study enrollment*.

    • Intoxication at the time of visit will exclude participation at that time. Participants cannot be visibly under the influence of substances at the time of enrollment or consent. If a participant returns to enroll while sober, enrollment can occur. Similarly, if a participant arrives to an intervention group visibly intoxicated, then she will be asked to leave. However, prior intoxication does not eliminate future participation. Thus, those who are dismissed from a session due to intoxication can return to a subsequent session as long as they are sober.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Compare pre-intervention, immediate post-intervention, and 3-month post-intervention scores on sexual risk and psychological empowerment1 year

Compare pre-intervention ACASI scores on Sexual Activity and Sexual Risk and Psychological Empowerment Questionnaires with those collected immediately post-intervention and 3 months after intervention to determine effect of intervention on sexual risk and psychological empowerment.

Secondary Outcome Measures
NameTimeMethod
Compare pre-intervention, immediate post-intervention, and 3-month post-intervention scores on self-efficacy, sexual negotiation, relational violence, forgiveness, anger, substance use, life goals and outcomes, and affect regulation1 year

Compare pre-intervention ACASI scores on three self-efficacy scales, two sexual negotiation scales, the Rosenberg Self-Esteem Scale, the CTS2, the HFS, the TAS, the ASSIST, a life goals/outcomes scale, and the Affect Regulation Scale with those collected immediately post-intervention and 3 months after intervention to determine effect of intervention on sexual risk and psychological empowerment.

Trial Locations

Locations (3)

USF College of Medicine

🇺🇸

Tampa, Florida, United States

University of Maryland Medical School

🇺🇸

Baltimore, Maryland, United States

Ruth M Rothstein CORE Center/ John H Stroger Jr Hospital

🇺🇸

Chicago, Illinois, United States

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