Predictive risk factors for pancreatic fistula grade C after pancreaticoduodenectomy: prospective large observational study
- Conditions
- Patients who undergo pancreaticoduodenectomy for pancreatic or periampullary lesions
- Registration Number
- JPRN-UMIN000015942
- Lead Sponsor
- Japanese Society of Hepato-Biliary-Pancreatic Surgery
- Brief Summary
Among 2762 patients, 46 patients (1.7%) developed Grade C POPF after PD. The mortality rate of the 46 patients with Grade C POPF was 37.0%. On the multivariate analysis, six independent risk factors for Grade C POPF were found; BMI > 25.0 kg/m2 , chronic steroid use, preoperative serum albumin <3.0 mg/dL, soft pancreas, operative time >480 minutes, and intraoperative transfusion. The c-statistic of our risk scoring model for Grade C POPF using these risk factors was 0.77.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 3022
Not provided
1) patients with severe respiratory disorder required oxygen inhalation 2) patients with severe liver dysfunction 3) patients with chronic renal failure with dialysis 4) patients who are unfit for this study as determined by the attending physician 5) patients requiring resection of other organs during pancreaticoduodenectomy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method