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临床试验/CTRI/2025/12/099047
CTRI/2025/12/099047尚未招募4 期

Comparison of intracuff Dexamethasone vs Normal saline for attenuation of post-extubation laryngotracheal morbidity.

Government of Gujarat1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2025年12月26日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
74
试验地点
1

研究概览

简要总结

Endotracheal intubation with cuffed tubes can cause laryngotracheal irritation and post-extubation symptoms such as cough, sore throat and hoarseness. Intracuff drug instillation may reduce these complications by reducing mucosal inflammation and preventing rise in cuff pressure.

This randomized placebo-controlled clinical trial aims to compare the effectiveness of intracuff dexamethasone versus normal saline in reducing post-extubation airway morbidity in adult patients undergoing elective laparoscopic surgeries under general anaesthesia.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Outcome Assessor Blinded

入排标准

年龄范围
20.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • ASA I, II, III Mallampati I and II Supine or trendelenberg position Duration: 2 to 3 hours Elective laparoscopic surgeries under GA with cuffed ETT.

排除标准

  • Refusal to consent ASA IV–V Mallampati III–IV Preexisting hoarseness, URI Steroid use, COPD, Asthma Known allergy to study drugs.

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Rutviksinh D Jadeja

B.J. Medical College & Civil Hospital.

研究点 (1)

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