CTRI/2025/12/099047尚未招募4 期
Comparison of intracuff Dexamethasone vs Normal saline for attenuation of post-extubation laryngotracheal morbidity.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 74
- 试验地点
- 1
研究概览
简要总结
Endotracheal intubation with cuffed tubes can cause laryngotracheal irritation and post-extubation symptoms such as cough, sore throat and hoarseness. Intracuff drug instillation may reduce these complications by reducing mucosal inflammation and preventing rise in cuff pressure.
This randomized placebo-controlled clinical trial aims to compare the effectiveness of intracuff dexamethasone versus normal saline in reducing post-extubation airway morbidity in adult patients undergoing elective laparoscopic surgeries under general anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA I, II, III Mallampati I and II Supine or trendelenberg position Duration: 2 to 3 hours Elective laparoscopic surgeries under GA with cuffed ETT.
排除标准
- •Refusal to consent ASA IV–V Mallampati III–IV Preexisting hoarseness, URI Steroid use, COPD, Asthma Known allergy to study drugs.
研究者
Dr Rutviksinh D Jadeja
B.J. Medical College & Civil Hospital.
研究点 (1)
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