Effects of Combining Cognitive and Treadmill Training on Cognitive Function and Walking Performance-Exploration in Chronic Stroke Patient With Cognitive Impairment
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- National Yang Ming Chiao Tung University
- Enrollment
- 8
- Locations
- 1
- Primary Endpoint
- Clock drawing test
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Post-stroke cognitive impairment is common in stroke survivors. Cognitive function is related to walking ability. The dual task walking is required for daily activities, however, such ability is even more challenging than single walking for people with stroke. The purpose of present study is to investigate the effects of combining cognitive and treadmill training on cognitive function and dual task walking performance in chronic stroke patients with cognitive impairment.
Detailed Description
This is a single-blinded, randomized controlled trial with pre- and post-measurements. 24 subjects will be recruited, and randomly assigned to one of two groups: cognitive training during treadmill training group (experimental group) and treadmill training group (control group). The intervention for both group will be 30 minutes per session, 3 sessions per week for a total of 4 weeks. Statistical data analysis will use the SPSS 25.0. Baseline characteristics will be analyzed using independent t-test or Chi-square test. Repeated measures two-way analysis of variance (ANOVA) with Tukey's post-hoc analysis will be used to compare between time and groups. The significant level is set at 0.05.
Investigators
Eligibility Criteria
Inclusion Criteria
- •age over 50 years old
- •chronic stroke (onset \>6 months)
- •with mini-mental state examination (MMSE) score≧24
- •Montreal cognitive assessment (MoCA) score\<26 (impaired cognition)
- •ability to walk independently for at least 10 meters without assistive devices or support
- •ability to read and write cognitive tests
Exclusion Criteria
- •diagnosis of dementia
- •unstable physical condition
- •any neurological, psychiatric disorder, or diagnosed with learning disability which may affect participation in this study
- •visual or auditory disturbances
Outcomes
Primary Outcomes
Clock drawing test
Time Frame: 10 minutes
visuospatial function (score 1-10)
Trail-making test A&B
Time Frame: 8 minutes
executive function (s)
Digit span test
Time Frame: 8 minutes
memory (number)
Stroop test
Time Frame: 10 minutes
attention (number)
Secondary Outcomes
- Single walking performance- speed (cm/s)(3 minutes)
- Single walking performance-step time (s)(3 minutes)
- Cognitive dual task walking performance-cadence (steps/min)(3 minutes)
- Single walking performance-step length (cm)(3 minutes)
- Single walking performance-cadence (steps/min)(3 minutes)
- Cognitive dual task walking performance-speed (cm/s)(3 minutes)
- Cognitive dual task walking performance-step length (cm)(3 minutes)
- Cognitive dual task walking performance-dual task cost (%)(3 minutes)
- Cognitive dual task walking performance-step time (s)(3 minutes)