Penta-therapy for severe acute hyperlipidemic pancreatitis: a retrospective chart review

Shanghai General Hospital0 个研究点目标入组 88 人开始时间: 2017年4月25日最近更新: 2019年9月9日

适应症

试验速览

•1. Aged 18 to 85 years old
•2. Presented within 72 hours of the onset of pain
•3. AP diagnosis made according to the Atlanta classification
•4. Triglyceride levels of >1,000 mg/dL(11.3mmol/L),>500mg/dL(5.65mmol/L) with lipidic plasma and no other obvious cause of pancreatitis found for HL-SAP patients
•5. Agree to participate and provide signed consent

•1. Flare-up of chronic pancreatitis
•2. History of allergies to heparin or insulin
•3. Disseminated intravascular coagulation or severe active bleeding
•4. Respiratory failure, severe systemic circulatory failure, coma, or other life-threatening symptoms that were difficult to reverse and who were predicted to die within 24 hours (with full-fluid resuscitation and norepinephrine usage at a dose of 25 mg/ min, with a systolic blood pressure <90 mm Hg and serum pH values <7.0)
•5. Patients who were delayed getting treatment because of some reason
•6. Patients who presented with APACHE II score <3

发起方