Impact of Respiratory Allergy on Response to Initiation of Biotherapy in Severe Asthma in Adult Severe Asthmatic Patients Followed at Poitiers University Hospital on Biotherapy

• Conditions: Severe Asthma; Biotherapy; Respiratory Allergy

• Registration Number: NCT06916104
• Lead Sponsor: Poitiers University Hospital

Brief Summary

The aim of this study is to take stock of the situation of adult patients with severe asthma on biotherapy, followed up at Poitiers University Hospital, and in particular to increase our knowledge of factors predictive of response to biotherapy. The main aim is to improve the management of adult severe asthma patients treated with biotherapy, according to their allergic status.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-01
• Status Verified: 2025-03
• Primary Completion: 2025-03-31
• Study Completion: 2025-03-31
• Study First Submitted: 2025-03-31
• Study First Submitted QC: 2025-03-31
• Last Update Submitted: 2025-03-31
• Study First Posted: 2025-04-08
• Last Update Posted: 2025-04-08

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Severe asthma patient on biotherapy
• Age > or = 18 years
• Follow-up at Poitiers University Hospital

Exclusion Criteria

• Absence of allergological assessment
• Patient's refusal to participate in study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Find out whether a positive respiratory allergy test influences the efficacy of one or more biotherapies	1 year

Secondary Outcome Measures

Name	Time	Method
analyze the allergological workup, particularly with regard to common pneumallergens	1 year
look at the response to the biotherapy used	1 year

Trial Locations

Locations (1)

Chu Poitiers; 🇫🇷 Poitiers, France