Calprotectin in patients with perianal fistulas: the CANALS study

none0 个研究点目标入组 70 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

•Crohn's perianal fistulas:
•Patients = 16 years old
•Established Crohn diagnosis, based on a combination of history, physical examination, family history, laboratory tests, endoscopy tests including histopathologic examination of mucosal bi-opsies, imaging studies and occasionally intraoperative findings
•Active perianal fistula as defined by spontaneous drainage or drainage upon gentle finger com-pression
•Clinical indication for surgical examination or intervention under anesthesia at discretion of the treating physician at the outpatients surgery center of the Amsterdam UMC, location AMC
•Written informed consent
•Cryptoglandular perianal fistulas:
•Patients = 16 years old
•Established diagnosis of a cryptoglandular perianal fistula, based on a combination of history and physical examination and supplemented by the prior exclusion of Crohn’s disease by at least one previous endoscopy
•Active perianal fistula as defined by spontaneous drainage or drainage upon gently finger com-pression
•Clinical indication for surgical examination or intervention under anesthesia at discretion of the treating physician at the outpatients surgery center
•Written informed consent

•Crohn's perianal fistulas:
•Age < 16 years at inclusion
•Perianal abscess > 2cm on MRI and/or clear clinical signs of an perianal abscess that requires surgical incision and drainage.
•Perianal hidradenitis suppurativa
•Clinical signs of an infectious gastroenteritis
•Patients with an ileostomy or colostomy
•No internal opening during surgical examination
•Cryptoglandular perianal fistulas:
•Age < 16 years at inclusion
•Perianal abscess
•Perianal hidradenitis suppurativa
•Clinical signs of an infectious gastroenteritis
•No internal opening during surgical examination

发起方

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