Assessment of Collagen Loaded With Bone Marrow Aspirate Concentrate Versus Autograft on Marginal Bone Changes Around Immediate Implants in Esthetic Zone. A Randomized Controlled Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- BMAC/ collagen
- Conditions
- Implant Site Reaction
- Sponsor
- Cairo University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Marginal bone changes
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla.
Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups:
study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants.
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Detailed Description
The aim of present study is to evaluate the effect of utilization of bone marrow aspirate concentrate (BMAC) loaded on collagen on the marginal bone changes around immediate implants in the esthetic zone of maxilla. Methodology: Twenty dental implants will be installed in patients suffering from non- restorable teeth in esthetic zone. Patients will be randomly divided into two equal groups: study group: The jumping gap surrounding the immediate implants will be grafted with bone marrow aspirate concentrate loaded on collagen, whereas in the control group, autogenous bone graft from the chin will be used to fill the peri-implant defect. CBCT will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around dental implants. .
Investigators
Walaa Kadry
Lecturer of oral and Maxillofacial Surgery
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Patients with non- restorable teeth in esthetic zone
- •Patients above 18 us
- •Highly motivated patients.
Exclusion Criteria
- •patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders
Arms & Interventions
BMAC/ collagen
Bone marrow aspirate concentrate loaded on collagen utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone
Intervention: BMAC/ collagen
Autograft
Autograft harvested from chin utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone
Intervention: Autograft harvesting from chin
Outcomes
Primary Outcomes
Marginal bone changes
Time Frame: 4 months
Buccal bone height