Assessment of Collagen Loaded With Bone Marrow Aspirate Concentrate Versus Autograft on Marginal Bone Changes Around Immediate Implants in Esthetic Zone. A Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Marginal bone changes
研究概览
简要总结
The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla.
Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups:
study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants.
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详细描述
The aim of present study is to evaluate the effect of utilization of bone marrow aspirate concentrate (BMAC) loaded on collagen on the marginal bone changes around immediate implants in the esthetic zone of maxilla.
Methodology: Twenty dental implants will be installed in patients suffering from non- restorable teeth in esthetic zone.
Patients will be randomly divided into two equal groups:
study group: The jumping gap surrounding the immediate implants will be grafted with bone marrow aspirate concentrate loaded on collagen, whereas in the control group, autogenous bone graft from the chin will be used to fill the peri-implant defect. CBCT will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around dental implants.
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研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with non- restorable teeth in esthetic zone
- •Patients above 18 us
- •Highly motivated patients.
排除标准
- •patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders
研究组 & 干预措施
BMAC/ collagen
Bone marrow aspirate concentrate loaded on collagen utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone
干预措施: BMAC/ collagen (Drug)
Autograft
Autograft harvested from chin utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone
干预措施: Autograft harvesting from chin (Procedure)
结局指标
主要结局
Marginal bone changes
时间窗: 4 months
Buccal bone height
次要结局
未报告次要终点
研究者
Walaa Kadry
Lecturer of oral and Maxillofacial Surgery
Cairo University