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Prospective Post-market Clinical Follow-up Study of the HBS 2 Resorb Mg in Patients With Intra- and Extraarticular Fractures, Pseudarthroses and Arthrodesis of Small Bones and Bone Fragments.

Phase 4
Recruiting
Conditions
Intraarticular Fracture
Pseudarthrosis
Arthrosis
Extraarticular Fracture
Interventions
Device: Treatment with HBS 2 Resorb Mg
Registration Number
NCT05483387
Lead Sponsor
KLS Martin
Brief Summary

This study is a multi-centre, prospective, clinical observational study to evaluate the CE-marked HBS 2 Resorb Mg screws under routine conditions. The device will be used according to its intended use. The data collected for this study does only include measurements which are standard of care.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Patient is 18 years and older
  • Patient is undergoing surgery with HBS 2 Resorb Mg
  • Written informed consent obtained for the treatment
  • Treatment of intra-articular and extra articular fractures and pseudarthroses of small bones and bone fragments as well as arthrodeses in the treatment of:
  • Scaphoid fractures and scaphoid pseudarthroses
  • Proximal radius head fractures
  • Fractures of the radial styloid process
  • Fractures of the ulnar styloid process
  • Metacarpal fractures
  • Metatarsal fractures
Exclusion Criteria
  • Any not medically managed severe systemic disease
  • Recent history of substance abuse (i.e. recreational drugs, alcohol) that would preclude reliable assessment
  • Pregnancy or women planning to conceive within the study period
  • Persons who are legally detained in an official institution
  • Participation in any other medical device or medicinal product study within the previous month that could influence the results of the present study
  • Skeletally immature
  • Intraoperative decision to use implants other than the device under investigation

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
HBS 2 Resorb MgTreatment with HBS 2 Resorb MgStudy arm treated with the HBS 2 Resorb Mg.
Primary Outcome Measures
NameTimeMethod
Bony Fusion (Change)6 weeks, 12 weeks, 6 month and 12 month after surgery

The primary endpoint of the study is the fusion rate of the bone. After the onset of bony fusion, the implant no longer fulfils any function, and it should be resorbed.

Secondary Outcome Measures
NameTimeMethod
Surgical revisions(YES/NO)6 weeks, 12 weeks, 6 month and 12 month after surgery

As typically one single surgery should be sufficient to treat the patient, all secondary surgical interventions are revisions due to a complication. This includes also re-operation due to screw removal.

Secondary displacement and breakage of the implant (YES/NO)6 weeks, 12 weeks, 6 month and 12 month after surgery

Any secondary radiographic displacement or breakage of the implant or any clinically significant loss of reduction is noted.

Clinical outcome6 weeks, 12 weeks, 6 month and 12 month after surgery

Patient pain (VAS) and outcome measures (Patient Related Outcome Measure) will be noted in order to assess patient satisfaction.

Early corrosion phenomenon(YES/NO)6 weeks, 12 weeks, 6 month and 12 month after surgery

Symptomatic gas accumulation or formation of gas pockets due to degradation of the material.

Deep infection(YES/NO)6 weeks, 12 weeks, 6 month and 12 month after surgery

The presence of deep infections is assessed binary.

Radiolucency(YES/NO)6 weeks, 12 weeks, 6 month and 12 month after surgery

Any radiolucency on the postoperative X-rays are noted. Radiolucency will be assessed by the operating surgeon.

Trial Locations

Locations (1)

Centrum für Muskuloskeletale Chirurgie (CMSC)

🇩🇪

Berlin, Germany

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