Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
- Conditions
- Surgical Site InfectionSternal Wound Infection
- Registration Number
- NCT04592328
- Lead Sponsor
- Region Örebro County
- Brief Summary
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation. Secondly, to compare if different regimes of antibiotics affects the bacterial growth.
Cultures will be taken from the skin, subcutaneous, and from the implanted valve prostheses with a rayon swab.Graft and Felt material will, after being pressed subcutaneous for 15 sec, placed into prepared sterile bottles containing broth for aerobe and anaerobe cultures. Surgical gloves will be cultured.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- Open cardiac surgery; coronary artery bypass grafting, valve replacement/repair or a combination of these.
- Skin conditions such as eczema, psoriasis.
- Revision surgery
- Aortic surgery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bacterial growth, C acnes Five months Growth of C acnes in cultures taken both from patients and surgical materials used in the primary operation.
Bacterial growth, other Five months Growth of bacteria in cultures taken both from patients and surgical materials
- Secondary Outcome Measures
Name Time Method Difference between subgroups Five months Difference in bacterial growth between subgroups.
Trial Locations
- Locations (1)
Örebro University hospital
🇸🇪Örebro, Sweden
Örebro University hospital🇸🇪Örebro, Sweden