The Presence of Skin Bacteria in the Sternal Wound and Their Possible Ability to Contaminate Implantation Materials During Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Bacterial growth, C acnes
研究概览
简要总结
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation. Secondly, to compare if different regimes of antibiotics affects the bacterial growth.
Cultures will be taken from the skin, subcutaneous, and from the implanted valve prostheses with a rayon swab.Graft and Felt material will, after being pressed subcutaneous for 15 sec, placed into prepared sterile bottles containing broth for aerobe and anaerobe cultures. Surgical gloves will be cultured.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Open cardiac surgery; coronary artery bypass grafting, valve replacement/repair or a combination of these.
排除标准
- •Skin conditions such as eczema, psoriasis.
- •Revision surgery
- •Aortic surgery
结局指标
主要结局
Bacterial growth, C acnes
时间窗: Five months
Growth of C acnes in cultures taken both from patients and surgical materials used in the primary operation.
Bacterial growth, other
时间窗: Five months
Growth of bacteria in cultures taken both from patients and surgical materials
次要结局
- Difference between subgroups(Five months)