Periodontal treatment for improving glycaemic control in diabetic patients: a randomised controlled trial

niversity Hospital of Toulouse (CHU de Toulouse) (France)0 个研究点目标入组 91 人开始时间: 2009年4月30日最近更新: 2019年11月25日

试验速览

•1. Male or female, aged >= 18 year old
•2. Diabetes mellitus (type I or II), diagnosed since at least one year
•3. HbA1c levels comprised between 7.0 and 9.5%
•4. No change in diabetic medication 3 months before inclusion
•5. Periodontal disease (at least one site on at least 4 teeth with Probing Pocket Depth >= 4 mm AND Clinical Attachment Loss >= 3 mm)
•6. At least 6 remaining teeth
•7. Subject able to understand and willing to provide written informed consent in French
•8. Subject affiliated to the security system

•1. Receiving antibiotherapy or chronic steroid therapy
•2. Presence of significant renal disease, as indicated by creatinine clearance less than 60 ml/min
•3. Have another medical condition likely to cause hospitalisation within 4 months
•4. Presence of serious or unstable infectious disease, hepatic disease, phenylcetonuria
•5. Subject at risk of endocarditis
•6. Pacemaker
•7. Antithrombotic treatment
•8. History of allergy to amoxicillin and clindamycin
•9. Pregnant, lactating, or plans to become pregnant during the study
•10. Participation in another study with an investigational compound

发起方

niversity Hospital of Toulouse (CHU de Toulouse) (France)