sing Computer-Aided polyp detection system (CADe) to maintain the high quality in adenoma detection rate during community-based colorectal cancer screening in Thailand: A randomized trial
Phase 3
Completed
- Registration Number
- TCTR20240710001
- Lead Sponsor
- Phrachomklao Hospital, Phetchaburi Province
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
1. All participants with age 50-75 years
Exclusion Criteria
1. Genetic disorders increasing colon cancer risk, such as familial adenomatous polyposis, Lynch syndrome, or past colon cancer.
2. Inflammatory bowel disease (IBD).
3. History of colon surgery.
4. Abnormal symptoms: bloody stools, alternating constipation and diarrhea, unexplained anemia, or weight loss.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ADR 2 weeks after colonoscopy and pathology reported Adenoma detection rate is percentage of patients undergoing screening colonoscopy, who have one or more precancerous polyps detected.
- Secondary Outcome Measures
Name Time Method proximal adenoma detection rate (pADR), advanced adenoma detection rate (AADR), and the number of adenomas/proximal adenomas/advanced adenomas per colonoscopy (APC, pAPC, and AAPC, respectively) 2 weeks after colonoscopy and pathology reported pADR is ADR that adenoma detected proximal to the splenic flexure. AADR is ADR with adenoma larger than 10 mm in size or with high-grade dysplasia.APC is number of adenomas detected per colonoscopy.