A Study of Pressure and Flow Characteristics During Inspiration and Expiration Using BreatheMAX® in Healthy Subjects
- Conditions
- Healthy Subjects
- Interventions
- Device: BreatheMAX breathing device
- Registration Number
- NCT02847416
- Lead Sponsor
- Khon Kaen University
- Brief Summary
the aim of this study are to explore the characteristics of mean airway pressure, oscillatory amplitude and power spectral density (PSD) of oscillatory airway pressure that generate by various loaded and flow rate during expiration and inspiration in healthy subjects and to explore the best loaded and flow rate for airway secretion clearance using the BreatheMAX® device
- Detailed Description
For inspiratory group, the resistive load 3, 4, 5, 6 and 7 cm H2O were test with three flow rate: 0.2, 0.4, and 0.6 L/sec in each load. In each flow rate, the subjects were instructed to inspire as deeply as possible with steady flow rate for 3 seconds with end-inspiratory pause for 2-3 seconds through the inspiratory circuit and follow by passive exhalation. For expiratory group, the resistive load and flow rate were test similar inspiratory group. In each flow rate, the subjects were instructed to inspire as deeply as possible through the nose with end-inspiratory pause for 2-3 seconds and partially forced exhalation with reach to 1/3 of expiratory reserve volume (ERV) for at least 3 seconds through expiratory circuit
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
- the healthy subjects
- able to breathe against resistive load with the BreatheMAX device
- good conscious and cooperation
- fever
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description expiratory group BreatheMAX breathing device the subjects will be instructed to inspire as deeply as possible through the nose with end-inspiratory pause for 2-3 seconds and partially forced exhalation with reach to 1/3 of expiratory reserve volume (ERV) for at least 3 seconds through expiratory circuit Inspiratory group BreatheMAX breathing device the subjects will be instructed to inspire as deeply as possible with steady flow rate for 3 seconds with end-inspiratory pause for 2-3 seconds through the inspiratory circuit and follow by passive exhalation
- Primary Outcome Measures
Name Time Method PSD of oscillatory airway pressure 5 seconds during inspiration and expiration testing period
- Secondary Outcome Measures
Name Time Method oscillatory amplitude 5 seconds during inspiration and expiration testing period mean airway pressure 5 seconds during inspiration and expiration testing period
Trial Locations
- Locations (1)
Pulmonary research room of physical therapy department, Faculty of associated medical sciences, Khon Kaen University
🇹🇭Khon Kaen, Thailand