Comparison of 0.5 percent hyperbaric bupivacaine and 0.5 percent hyperbaric levobupivacaine with buprenorphine as an adjuvant for spinal anesthesia in adults undergoing infraumbilical surgeries – a one year hospital based randomized control trial.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- To study the effect of intrathecal buprenorphine as an adjuvant to 0.5% hyperbaric bupivacaine and 0.5% hyperbaric levobupivacaine on hemodynamic parameters (HR, SBP, DBP, MAP, SpO2 ) in adults undergoing infraumbilical surgeries under spinal anesthesia.
研究概览
简要总结
This study is being undertaken with the aim of comparing intrathecal buprenorphine as an adjuvant to 0.5% hyperbaric bupivacaine and 0.5% hyperbaric levobupivacaine for spinal anesthesia in adults undergoing infraumbilical surgeries. The purpose of this study is to compare the haemodynamic parameters and to compare the onset of sensory and motor block between two drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age 18-60 years Either gender American Society of Anesthesiologists (ASA) grade I and II patients Patients undergoing infraumbilical surgeries under spinal anesthesia.
排除标准
- •Patients with American Society of Anesthesiologists (ASA) grade III or more Patients with allergy to study drug.
结局指标
主要结局
To study the effect of intrathecal buprenorphine as an adjuvant to 0.5% hyperbaric bupivacaine and 0.5% hyperbaric levobupivacaine on hemodynamic parameters (HR, SBP, DBP, MAP, SpO2 ) in adults undergoing infraumbilical surgeries under spinal anesthesia.
时间窗: Pre operative, 0 minute, 5 minutes, 15 minutes
次要结局
- - To evaluate and compare the onset of sensory and motor blockade of intrathecal buprenorphine as an adjuvant to 0.5% hyperbaric bupivacaine and 0.5% hyperbaric levobupivacaine in adults undergoing infraumbilical surgeries under spinal anesthesia.(0 minute)
研究者
Dr Anul R Shinde
KLE Dr Prabhakar Kore Hospital and Medical Research Centre