A randomized controlled clinical trial to study the effect of tranexaemic acid in head neck surgery - none

il0 个研究点目标入组 92 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•Adult patients (minimum of eighty patients) suffering with different head and neck tumor (benign or malignant with/without nodal metastasis) undergoing different head neck surgeries under general anaesthesia will be enrolled after obtaining informed consent. These patients will be enrolled in two groups with each group having control.
•Group 1: Patients undergoing total thyroidectomy, total parotidectomy, comprehensive or selective neck dissection with or without primary tumour excision
•Group 2: Patient undergoing thyroid lobectomy or hemithyroidectomy and superficial parotidectomy without neck dissection.

•1. A history of preoperative chemotherapy or radiotherapy.
•2. Patients with allergic to tranexaemic acid
•3. Any coagulopathy/bleeding disorder/deep vein thrombosis/peripheral vascular diseases.
•4. Patients on anticoagulant / antiplatelet/ antifibrinolytic drugs
•5. Coronary artery disease, chronic renal insufficiency, hematuria, Uncontrolled hypertension
•6. Patients opting not to participate in the trial i.e. who do not give consent.

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