A clinical trial to study the effect of tranexaemic acid in head neck surgeries
- Conditions
- Health Condition 1: C07- Malignant neoplasm of parotid glandHealth Condition 2: null- Patients suffering with different head and neck cancers and fit to undergo surgeryHealth Condition 3: C775- Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes
- Registration Number
- CTRI/2017/10/010064
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 92
Adult patients (minimum of eighty patients) suffering with different head and neck tumor (benign or malignant with/without nodal metastasis) undergoing different head neck surgeries under general anaesthesia will be enrolled after obtaining informed consent. These patients will be enrolled in two groups with each group having control.
Group 1: Patients undergoing total thyroidectomy, total parotidectomy, comprehensive or selective neck dissection with or without primary tumour excision
Group 2: Patient undergoing thyroid lobectomy or hemithyroidectomy and superficial parotidectomy without neck dissection.
1. A history of preoperative chemotherapy or radiotherapy.
2. Patients with allergic to tranexaemic acid
3. Any coagulopathy/bleeding disorder/deep vein thrombosis/peripheral vascular diseases.
4. Patients on anticoagulant / antiplatelet/ antifibrinolytic drugs
5. Coronary artery disease, chronic renal insufficiency, hematuria, Uncontrolled hypertension
6. Patients opting not to participate in the trial i.e. who do not give consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of tranexaemic acid in reduction of postoperative surgical drainTimepoint: 3 days after surgery
- Secondary Outcome Measures
Name Time Method