Contribution of Transnasal Humidified Rapid-insufflation Ventilatory Exchange (THRIVE) to Optimize Maternal Pre-oxygenation and Anaesthetic Preparation Time for General Anaesthesia for Urgent Caesarean Section A Prospective Experimental Study on Healthy Volunteers.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- time between when the volunteer enters the operating room and when the conditions for general anesthesia are met during pre-oxygenation
研究概览
简要总结
The main objective of this study is to determine if the use of transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) can reduce by 90 seconds the time between the entry into the operating room of the volunteer and the moment when the anaesthetic drugs are ready and when the Oxygen Reserve Index has reached a plateau value for more than 10 seconds, a moment which would therefore allow the induction of general anaesthesia, compared to the pre-oxygenation with the face mask applied by the anaesthetist alone in charge of anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •affiliated to a social security scheme or beneficiary of such a scheme
- •having voluntarily and informedly agreed to participate in the study.
- •non-smoker
- •free from pulmonary, cardiac and neurological pathologies
- •have a normal functional respiratory test at baseline.
排除标准
- •refusal to participate in the study
- •non-French speaking volunteer
- •obesity defined by a body mass index greater than 30 kilogram/meter² (kg/m²)
- •current pregnancy
- •Volunteer in period of exclusion from further research
- •Person under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights and liberty
结局指标
主要结局
time between when the volunteer enters the operating room and when the conditions for general anesthesia are met during pre-oxygenation
时间窗: through study completion, an average of 1 year
Difference between the time when volunteer enters the operating room and the time when the conditions for general anaesthesia are met during pre-oxygenation with the face mask applied by one anaesthesist in charge of the volunteer (simulated patient) compared to the use of preoxygenation with THRIVE by one anaesthesist in charge of the volunteer
次要结局
- number of medication errors during the preparation(through study completion, an average of 1 year)
- number of deviations from appropriate anaesthetic practices observed during preparation(through study completion, an average of 1 year)
- time between volunteer enters the operating room and when the conditions for general anaesthesia are met during pre-oxygenation(through study completion, an average of 1 year)