Contribution of Transnasal Humidified Rapid-insufflation Ventilatory Exchange (THRIVE) to Optimize Maternal Pre-oxygenation and Anaesthetic Preparation Time for General Anaesthesia for Urgent Caesarean Section A Prospective Experimental Study on Healthy Volunteers.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cesarean Section Complications
- Sponsor
- Hospices Civils de Lyon
- Enrollment
- 1
- Locations
- 1
- Primary Endpoint
- time between when the volunteer enters the operating room and when the conditions for general anesthesia are met during pre-oxygenation
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The main objective of this study is to determine if the use of transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) can reduce by 90 seconds the time between the entry into the operating room of the volunteer and the moment when the anaesthetic drugs are ready and when the Oxygen Reserve Index has reached a plateau value for more than 10 seconds, a moment which would therefore allow the induction of general anaesthesia, compared to the pre-oxygenation with the face mask applied by the anaesthetist alone in charge of anaesthesia.
Investigators
Eligibility Criteria
Inclusion Criteria
- •affiliated to a social security scheme or beneficiary of such a scheme
- •having voluntarily and informedly agreed to participate in the study.
- •non-smoker
- •free from pulmonary, cardiac and neurological pathologies
- •have a normal functional respiratory test at baseline.
Exclusion Criteria
- •refusal to participate in the study
- •non-French speaking volunteer
- •obesity defined by a body mass index greater than 30 kilogram/meter² (kg/m²)
- •current pregnancy
- •Volunteer in period of exclusion from further research
- •Person under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights and liberty
Outcomes
Primary Outcomes
time between when the volunteer enters the operating room and when the conditions for general anesthesia are met during pre-oxygenation
Time Frame: through study completion, an average of 1 year
Difference between the time when volunteer enters the operating room and the time when the conditions for general anaesthesia are met during pre-oxygenation with the face mask applied by one anaesthesist in charge of the volunteer (simulated patient) compared to the use of preoxygenation with THRIVE by one anaesthesist in charge of the volunteer
Secondary Outcomes
- number of medication errors during the preparation(through study completion, an average of 1 year)
- number of deviations from appropriate anaesthetic practices observed during preparation(through study completion, an average of 1 year)
- time between volunteer enters the operating room and when the conditions for general anaesthesia are met during pre-oxygenation(through study completion, an average of 1 year)