The Glucose Tolerance Test Study
Phase 4
Completed
- Conditions
- Anti-inflammatory effect of insulin after Oral versus intravenous glucose in overweight individuals.Overweight/obesityMetabolic and Endocrine - Normal metabolism and endocrine development and function
- Registration Number
- ACTRN12612000491864
- Lead Sponsor
- niverstiy of otago
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
BMI > 27kg/m2 , have no ongoing health problems, not have diabetes, take no medication.
Exclusion Criteria
Smoking, diabetes. Taking medications. BMI < 27kg/m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma level of IL-6 will be measured at 5 points after the glucose and water are given.[These levels will be measured in blood samples taken at 0, 30, 60, 90 and 120 minutes.]
- Secondary Outcome Measures
Name Time Method We will expand available information on the acute anti-inflammatory effect of insulin which may be important in limiting the inflammatory effect of food by measuring changes in plasma IL-6 levels.[proposed publication of results in peer reviewed journals 2012]