Altered breathing with postoperative pain relief

Phase 3

• Conditions: Respiratory Depression; Diet and Nutrition - Obesity; Respiratory - Pain management; Obesity; Postoperative analgesia

• Registration Number: ACTRN12607000208404
• Lead Sponsor: Royal Melbourne Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-04-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Obese (BMI>29) patients or airway abnormality on preoperative anaesthesia examination.Likely to require postoperative morphine or equivalent analgesia.Postoperative overnight hospital stay.

Exclusion Criteria

Intrathoracic or upper-abdominal surgery. Previous adverse reaction to any study drugs including nausea or vomiting.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduced number respiratory obstructions or desaturations.[Total for 12 hours to 0600hr on day after surgery.]

Secondary Outcome Measures

Name	Time	Method
Analgesia and side-effects[Average of verbal numeric pain scores for 12hr period to 0600hr, need for rescue analgesia.]