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Clinical Trials/NCT02782832
NCT02782832
Completed
Not Applicable

No Need for Neuromuscular Blockade in Day Case Standardised Laparoscopic Surgery. A Consecutive Retrospective Study

Hvidovre University Hospital0 sites1,245 target enrollmentMay 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cholecystitis
Sponsor
Hvidovre University Hospital
Enrollment
1245
Primary Endpoint
Number of patients requiring neuromuscular blockade
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic surgery setting and analyse specific reasons for using neuromuscular blockade in individual patients. Furthermore, the study report the analgesic use in postoperative care unit and the discharge rate.

Detailed Description

The study is retrospective, including consecutive patients in an unrestricted referral of patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair. Inclusion period was from 01.04.2013 to 31.03.2015. All patients received general anesthesia using propofol (2 mg/kg) and remifentanil (1 μg/kg/min) for induction. In patients where tracheal intubation was required, this was done without use of neuromuscular blocking drug; otherwise a proseal laryngeal mask was used. For the maintenance of anesthesia, additional continuous infusion of propofol (3-5 mg/kg/h) and remifentanil (0.3-0.5 μg/kg/min) was used. Data were derived from a prospective local database on demographics, anesthetic methods and supplements (i.e. need for neuromuscular blockade) and postoperative needs for supplementary analgesics besides the postoperative standard analgesic regimen, number of hours stayed in the ambulatory surgery department, and discharge rate (including reasons for hospital admittance).

Registry
clinicaltrials.gov
Start Date
May 2016
End Date
August 2016
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Billy B Kristensen

Chief Physician

Hvidovre University Hospital

Eligibility Criteria

Inclusion Criteria

  • patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Number of patients requiring neuromuscular blockade

Time Frame: At time of surgery

Data derived from a prospective local database on need for neuromuscular blockade in patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair.

Secondary Outcomes

  • Analgesic use in postoperative care unit(Within 6 hours after surgery)
  • Hours stayed in the postoperative care unit(1 to 6 hours after surgery)
  • Maximum Visual analog score (VAS) for pain in the postoperative Care unit(1 to 6 hours after surgery)

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