NCT04062864
Completed
Not Applicable
Validity of Pupil Diameter for Pain Monitoring During General Anesthesia in Children : a Prospective Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anesthesia, General
- Sponsor
- Seoul National University Hospital
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- Pupil diameter
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
This study evaluates the validity of pupil diameter as an indicator of pain during surgery under general anesthesia.
Detailed Description
Pupil diameter is known to be strongly correlated with sympathetic tone. During surgery under general anesthesia, there is no standardized means of pain assessment. As pain activates sympathetic nervous system, we hypothesized that pupil diameter can be a marker for pain during surgery.
Investigators
Hee-Soo Kim
Professor
Seoul National University Hospital
Eligibility Criteria
Inclusion Criteria
- •Children undergoing surgery under general anesthesia with total time of less than two hours
Exclusion Criteria
- •Children whose parent or legal guardian declined to enroll
- •Any use of opioids during surgery
- •History of hypersensitivity to any anesthetic agents
- •Any medication that can affect sympathetic nervous activity
- •Presence of underlying ophthalmologic disease
Outcomes
Primary Outcomes
Pupil diameter
Time Frame: From start of anesthesia to end of anesthesia
Pupil diameter before and after painful stimuli (skin incision, train-of-four stimulation)
Secondary Outcomes
- Bispectral index(From start of anesthesia to end of anesthesia)
- Pleth variability index(From start of anesthesia to end of anesthesia)
Study Sites (1)
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