Association of Plasma Transfusions and Invasive Fungal Infection
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- the rate of invasive fungal infection
研究概览
简要总结
Although lacking strong evidences, plasma transfusions are commonly used in critically ill neonates. To date, the relationships between plasma transfusions and nosocomial infection remain controversial and no study has reported the relationships between plasma transfusion and invasive fungal infection (IFI)
详细描述
Our aim is to explore the association between plasma transfusions and IFI in critically ill neonates
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Hours 至 24 Hours（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all critically ill neonates admitted in hospital
排除标准
- •severe congenital abnormality;
- •died within 24 hours or left neonatal intensive care unit within 24 hours according to their parents' decisions;
- •parents' decision not to participate.
研究组 & 干预措施
non-plasma transfusions
The critical ill neonates without plasma transfusions
干预措施: non-plasma transfusions (Drug)
plasma transfusions
The critical ill neonates with plasma transfusions
干预措施: plasma transfusions (Drug)
结局指标
主要结局
the rate of invasive fungal infection
时间窗: 100 days
the rate of invasive fungal infection in plasma transfusions group
次要结局
未报告次要终点
研究者
Ma Juan
director
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University