Effect of two different dressings on palatal wound healing

Completed

• Conditions: Patients requiring free gingival graft for increasing width of attached gingiva or recession coverage

• Registration Number: CTRI/2017/01/007719
• Lead Sponsor: Institute of Dental Studies and Technologies

Brief Summary

This study was conducted and compiled by Dr.Varsha Sharma, Dr.Ashish Kumar, Dr.Komal Puri, Dr.Mansi Bansal and Dr.Manish Khatri at Department Of Periodontology, Institute of Dental Studies and Technologies, Kadrabad, Modinagar, Uttar Pradesh, India

The study is a randomized control trial for comparison of the effect of commercially available collagen dressing (colla cote®) and autologous platelet rich fibrin on the wound healing of palatal donor site of free gingival graft.  Assessment and comparison of various wound healing parameters, time required for complete epithelization of wound and considerable morbidity during the healing period was done.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-05-05
• Last Update Posted: 2017-01-16

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1)Systemically healthy patients aged 18 years or more, 2)Patient not under any medication for the past six months, 3)Patients requiring FGG either for reduced/ inadequate gingiva or gingival recession in the maxillary or mandibular anterior region, 4)Patients who have not undergone any palatal graft procedure in the past one year.

Exclusion Criteria

1)Smokers, 2)Pregnant or lactating mothers, 3)Patients not maintaining oral hygiene.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Immediate Bleeding	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Delayed Bleeding	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Pain Score	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Size of wound	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Depth of wound	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Toluidine blue test for epithelization	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Hydrogen peroxide test for epithelization	Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.

Trial Locations

Locations (1)

Institute of Dental Studies and Technologies; 🇮🇳 Ghaziabad, UTTAR PRADESH, India

Institute of Dental Studies and Technologies

🇮🇳Ghaziabad, UTTAR PRADESH, India

Dr Varsha Sharma

Principal investigator

08126021212

drsharmavarsha@gmail.com