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A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy

Phase 4
Completed
Conditions
Colonoscopy
Interventions
Drug: Split Dose Pico-Salax
Registration Number
NCT00885274
Lead Sponsor
Queen's University
Brief Summary

Pico-Salax is an osmotic and stimulant bowel cleansing agent used prior to colonoscopy. It is unknown whether splitting the doses (i.e. taking the second dose the morning of the colonoscopy) results in a better bowel cleansing, as research with other agents suggests this may be the case. This study aims to assess whether splitting the dose of Pico-Salax results in a better bowel cleansing than traditional dosing.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
250
Inclusion Criteria
  • colonoscopy indicated
Exclusion Criteria
  • congestive heart failure
  • ascites
  • renal failure
  • hyponatremia
  • previous intestinal surgery

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Split DoseSplit Dose Pico-SalaxDoses of Pico-Salax split: one dose administered the night prior to colonoscopy and the other dose administered the day of the procedure.
Traditional DosePico-SalaxBoth doses of Pico-Salax taken the evening prior to colonoscopy.
Primary Outcome Measures
NameTimeMethod
bowel cleansing assessed by the Ottawa Bowel Preparation Scaleday of colonoscopy
Secondary Outcome Measures
NameTimeMethod
patient tolerance of preparationday of colonoscopy

Trial Locations

Locations (1)

Hotel Dieu Hospital

🇨🇦

Kingston, Ontario, Canada

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