A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- bowel cleansing assessed by the Ottawa Bowel Preparation Scale
研究概览
简要总结
Pico-Salax is an osmotic and stimulant bowel cleansing agent used prior to colonoscopy. It is unknown whether splitting the doses (i.e. taking the second dose the morning of the colonoscopy) results in a better bowel cleansing, as research with other agents suggests this may be the case. This study aims to assess whether splitting the dose of Pico-Salax results in a better bowel cleansing than traditional dosing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •colonoscopy indicated
排除标准
- •congestive heart failure
- •renal failure
- •hyponatremia
- •previous intestinal surgery
研究组 & 干预措施
Split Dose
Doses of Pico-Salax split: one dose administered the night prior to colonoscopy and the other dose administered the day of the procedure.
干预措施: Split Dose Pico-Salax (Drug)
Traditional Dose
Both doses of Pico-Salax taken the evening prior to colonoscopy.
干预措施: Pico-Salax (Drug)
结局指标
主要结局
bowel cleansing assessed by the Ottawa Bowel Preparation Scale
时间窗: day of colonoscopy
次要结局
- patient tolerance of preparation(day of colonoscopy)
研究者
Dr. Lawrence Hookey
Assistant professor of Medicine
Queen's University