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Clinical Trials/NCT05765721
NCT05765721
Completed
Not Applicable

Development of Family-based Frailty Selfmanagement Model and the Effects of the FRAIL-SM Program Among Patients With Heart Failure

National Yang Ming Chiao Tung University2 sites in 1 country232 target enrollmentNovember 16, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Frailty
Sponsor
National Yang Ming Chiao Tung University
Enrollment
232
Locations
2
Primary Endpoint
Change in Frailty Assessment Scale for Heart Failure( FAS-HF) scores
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

This randomized controlled trial study aims to develop a frailty self-management model for heart failure patients, and to examine the effect of family-based frailty self-management program (FRAIL-SM) including Family involvement, self-Regulation, Autonomy support, Information sharing and Linkage on frailty, knowledge, self-care ability and quality of life in patients with heart failure and their family's strain, knowledge, confedence, and quality of life. Data is collected by a structural questionnaire including frailty, heart failure knowledge, self-care of heart failure, anxiety and depression, social support, and quality of life and physical indicators at baseline, 4 weeks, 8 weeks and 12 weeks after enrollment.

Detailed Description

This study aims to develop a frailty self-management model for heart failure patients, and to examine the effect of family-based frailty self-management program (FRAIL-SM) including Family involvement, self-Regulation, Autonomy support, Information sharing and Linkage on frailty, self-care ability and quality of life in patients with heart failure and their family's strain and quality of life. Patients are recruited with a convenience sampling from two medical centers in Taiwan. A cross-sectional study is adopted to examine the associated factors of frailty and self-management in patients with heart failure. Besides, a qualitative research with face-to-face individual interview is conducted to understand the experience of frailty and self-management in patients with heart failure and their families. Then, a randomized controlled trial is conducted. Subjects are selected using a convenience sampling and are randomly assigned to the intervention or control group. Patients in the intervention group will receive an 8-week family-based frailty self-management program. Data is collected by a structural questionnaire including frailty, heart failure knowledge, self-care of heart failure, anxiety and depression, social support, and quality of life and physical indicators such as levels of B-type natriuretic peptide, hemoglobin, hematocrit, albumin at baseline, 4 weeks, 8 weeks and 12 weeks after enrollment. Data analysis includes descriptive statistics, Pearson correlation coefficient, independent t-test, chi-square, one-way ANOVA, multiple regression, structural equation modeling, and generalized estimating equation.

Registry
clinicaltrials.gov
Start Date
November 16, 2023
End Date
October 1, 2024
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • aged ≥ 40 years.
  • diagnosed by doctros with heart failure and in stable condition.
  • clear consciousness, can communicate with Chinese and Taiwanese.
  • consent to join in this study.
  • have a smartphone or computer and be able to join social media
  • have SOF score ≥ 1

Exclusion Criteria

  • were bed-ridden or unable to perform activities of daily living independently.
  • diagnosed by doctors with cognitive dysfunction, mental illness, or severe depression
  • in the acute stage of the disease, such as inflammation, infection, or vascular embolism
  • with contraindications to exercise, such as those with uncontrolled arrhythmia, unstable heart rate, BP or PaO
  • suffer from neurological, muscular, skeletal or rheumatoid diseases that are aggravated by exercise.
  • Caregivers Inclusion Criteria:
  • aged ≥ 20 years.
  • clear consciousness, can communicate with Chinese and Taiwanese.
  • consent to join in this study with patients.
  • Caregivers Exclusion Criteria:

Outcomes

Primary Outcomes

Change in Frailty Assessment Scale for Heart Failure( FAS-HF) scores

Time Frame: baseline, 4week, 8week, 12week

Changes from baseline Frailty Assessment Scale for Heart Failure (FAS-HF) scores including three indicators: physical, Psychological and social , at 4 weeks, 8 weeks, 12 weeks. FAS-HF scale contains 15 items, each item use Likert scale five point scoring, the total scores ranged from 0 to 45,the higher scores indicate higher frailty.

Changes in The Minnesota living with heart failure questionnaire(MLHFQ) scores

Time Frame: baseline, 4week, 8week, 12week

Changes from baseline Minnesota living with heart failure questionnaire at 4 weeks, 8 weeks, 12 weeks. The Minnesota living with heart failure questionnaire contains 21 questions regarding the effects of heart failure on patients' physical (eight questions),emotional (five questions) and general (eight questions) dimensions. The possible answer for each question ranges from 0(no) to 5(a lot), and the total score range is 0-105; a higher score indicates lower quality of life .

Changes in the Self-Care of Heart Failure Index scores

Time Frame: baseline, 4 weeks, 8 weeks, 12 weeks

Changes from baseline Self-Care of Heart Failure Index scores including three indicators: self-maintenance, self-management and self confidence , at 4 weeks, 8 weeks, 12 weeks. This scale contains 22 items, each item use Likert scale four point scoring, the total scores ranged from 22 to 88, the higher scores indicate better self-care.

Secondary Outcomes

  • Changes in The Caregiver Strain Index(CSI)(baseline, 4week, 8week, 12week)
  • Changes in heart failure knowledge of caregivers(baseline, 4week, 8week, 12week)
  • Changes in caregivers' quality of life(baseline, 4week, 8week, 12week)
  • Changes in caregivers confidence of heart failure self care(baseline, 4week, 8week, 12week)
  • Changes in symptoms distress scores(baseline, 4week, 8week, 12week)
  • Changes in anxiety and depression scores(baseline, 4week, 8week, 12week)

Study Sites (2)

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