Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized- Control Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Postoperative pain
研究概览
简要总结
Postoperative pain and blood loss of non-use compared to partial-use of a tourniquet in bilateral total knee replacement: A Randomized- Control Trial This study aimed to compare the effects of non-use (NTU) and partial-use (before osteotomy to skin closure; BOO) of a tourniquet in bilateral total knee arthroplasty (TKA) on postoperative pain and complications.
详细描述
Despite numerous meta-analyses, and randomized-control trials (RCTs), there is still no conclusive evidence on the most effective, and efficient method of using a tourniquet.
There is gap of knowledge of method of tourniquet usage. Hence this study will provide the best method to apply tourniquet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessor will not know whether which group are using tourniquet.
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with over 50 years of age and diagnosed with bilateral severe knee osteoarthritis undergoing bilateral TKA
排除标准
- •patients having undergone previous knee surgery
- •patients being subject to uncontrolled hypertension, coagulopathy, or recent knee sepsis
- •patients with an ASA physical status grade > 2,
- •inability to use patient-controlled analgesia (PCA), such as communication, or cognitive issues, or those patients who were allergic to medications used in the treatment process.
研究组 & 干预措施
Non-use of a tourniquet (NTU)
No tourniquet is used throughout the surgery.
干预措施: None tourniquet (Procedure)
Partial-use of a tourniquet
Partial use of a tourniquet is throughout the surgery.
干预措施: None tourniquet (Procedure)
结局指标
主要结局
Postoperative pain
时间窗: At postoperative Day1,2,3,4
Morphine consumption and Visual analog scale for pain minimum 0, maximum 10
次要结局
- Blood loss(At postoperative Day1,2,3,4)