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临床试验/CTRI/2025/08/093384
CTRI/2025/08/093384尚未招募不适用

Music Rhythm-Intervention Targeting Attention in Stroke: A Neuropsychological and Electrophysiological Quasi-randomized Study.

NIMHANS1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年9月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
NIMHANS
入组人数
60
试验地点
1
主要终点
Attention functions as tested on neuropsychological tests and EEG/ERP paradigms

研究概览

简要总结

Stroke is a leading cause of long-term disability worldwide, with attention deficits being among the most common and functionally debilitating cognitive impairments. This quasi-randomized study aims to evaluate the efficacy of a rhythm-based intervention in enhancing attention among individuals with stroke. he study will be conducted at NIMHANS, Bengaluru, with stroke participants in the early sub-acute phase (7 days to 3 months post-stroke), aged 18–55 years, with first-ever anterior circulation strokes confirmed by CT/MRI. Age- and education-matched healthy controls will also be recruited. In Phase I, stroke patients will be compared with healthy controls on attention tasks using behavioral and EEG/ERP methods. In Phase II, stroke patients will be assigned to either a rhythm-based intervention group or an active control group (audiobook/story listening), each undergoing 15 sessions over three weeks. Primary outcomes include measurement of various attention domains, measured through computerized tasks and EEG indices. Secondary outcomes include assessment of various neuropsychological functions (including executive functions) and functional outcomes in stroke. Findings are expected to establish rhythm training as a novel, cost-effective adjunct to cognitive rehabilitation in stroke, with potential broader applicability across neurological conditions

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • First ever anterior circulation stroke confirmed by CT or MRI Early sub acute period at the time of intervention Age 18 to 55 years Ability to read and write at least one language.
  • Ability to comprehend English Hindi Tamil and Kannada.

排除标准

  • Co morbid neurological disorders Global or Receptive aphasia Hemineglect Audiovisual impairments Severe cognitive impairment as measured by a score of 10 or below on MoCA Medically unstable at the time of recruitment Unamenable for neuropsychological testing due to reasons not abovementioned Sub normal pre-morbid intellectual functioning as measured clinically History of formal music training.

结局指标

主要结局

Attention functions as tested on neuropsychological tests and EEG/ERP paradigms

时间窗: pre-post intervention. 3-4 weeks

次要结局

  • Other neurocognitive functions (including executive functions and memory)(pre-post intervention. 3-4 weeks)
  • Functional outcomes(pre-post intervention. 3-4 weeks)

研究者

发起方
NIMHANS
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Shreyas Krishnakumar

National Institute of Mental Health and Neurosciences

研究点 (1)

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