NCT01766973
Completed
Not Applicable
Observational Study to Determine Abnormalities in Resting State fMRI in Chronic Back Pain.
ConditionsChronic Back Pain
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Back Pain
- Sponsor
- University of Cambridge
- Enrollment
- 76
- Locations
- 1
- Primary Endpoint
- Functional brain connectivity
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.
Investigators
Dr Ben Seymour
Wellcome Intermediate Clinical Fellow
University of Cambridge
Eligibility Criteria
Inclusion Criteria
- •age 18-60
- •pain \> 6months
- •right-handed
- •non-smoking
- •mechanical back pain
Exclusion Criteria
- •significant neurological or psychiatric disease
- •major systemic illness
- •MRI exclusion criteria
Outcomes
Primary Outcomes
Functional brain connectivity
Time Frame: 6 months
Assessed by fMRI
Study Sites (1)
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