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Clinical Trials/NCT01766973
NCT01766973CompletedNot Applicable

Observational Study to Determine Abnormalities in Resting State fMRI in Chronic Back Pain.

University of Cambridge1 site in 1 country76 target enrollmentStarted: April 6, 2013Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
76
Locations
1
Primary Endpoint
Functional brain connectivity
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 60 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •age 18-60
  • •pain > 6months
  • •right-handed
  • •non-smoking
  • •mechanical back pain

Exclusion Criteria

  • •significant neurological or psychiatric disease
  • •major systemic illness
  • •MRI exclusion criteria

Outcomes

Primary Outcomes

Functional brain connectivity

Time Frame: 6 months

Assessed by fMRI

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Dr Ben Seymour

Wellcome Intermediate Clinical Fellow

University of Cambridge

Study Sites (1)

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