Decoding Chronic Pain With fMRI

Completed

• Conditions: Chronic Back Pain

• Registration Number: NCT01766973
• Lead Sponsor: University of Cambridge

Brief Summary

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-01-10
• Study First Submitted QC: 2013-01-10
• Study First Posted: 2013-01-11
• Study Start: 2013-04-06
• Primary Completion: 2016-04-06
• Status Verified: 2018-06
• Study Completion: 2018-06-06
• Last Update Submitted: 2018-06-06
• Last Update Posted: 2018-06-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

• age 18-60
• pain > 6months
• right-handed
• non-smoking
• mechanical back pain

Exclusion Criteria

• significant neurological or psychiatric disease
• major systemic illness
• MRI exclusion criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional brain connectivity	6 months	Assessed by fMRI

Trial Locations

Locations (1)

Addenbrookes Hospital; 🇬🇧 Cambridge, United Kingdom