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Efficacy of inhaled N-acetylcysteine(NAC) on lung function and redox balance in idiopathic pulmonary fibrosis(IPF).

Not Applicable
Conditions
Idiopathic pulmonary fibrosis
Registration Number
JPRN-UMIN000007663
Lead Sponsor
Toho University Omori Medical Center Department of Respiratory Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

1)Secondary interstitial pneumonia 2)Serious complication 3)Serious drug allergy 4)Mental disorder, central nervous system disorders, cerebrovascular disorders 5)Any other medical condition that makes the patient unsuitable for inclusion in the study according to the opinion of the investigator.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The changes in respiratory function test before and after the therapy.
Secondary Outcome Measures
NameTimeMethod
The levels of total GSH(tGSH), oxidized GSH(GSSG), and GSH/GSSG ratio in the peripheral blood, and 8-OHdG in the urine.
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