To characterize the incidence, impact, and risk factors of covert stroke in adults undergoing noncardiac surgery.
- Conditions
- Health Condition 1: G319- Degenerative disease of nervous system, unspecifiedHealth Condition 2: null- Patients undergoing non cardiac surgery
- Registration Number
- CTRI/2018/01/011502
- Lead Sponsor
- Population Health Research Institution
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 8
1. Age �65 years old
2. An anticipated hospital stay of at least 2 days after elective noncardiac surgery that occurs under general or neuraxial anesthesia
3. Written informed consent for potential participation prior to noncardiac surgery
1. Contraindication to MRI (e.g. implanted devices not safe for MRI studies, claustrophobia, unable to lie flat or still),
2. Unable or unwilling to attend the follow-up appointments,
3. Documented history of dementia
4. Residing in a nursing home,
5. Undergoing carotid artery surgery or intracranial surgery
6. Unable to complete neurocognitive testing due to language, vision or hearing impairment,
7. Unable to communicate with the research staff due to language barriers,
8. Previously enrolled in the NeuroVISION Study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Our primary outcome is postoperative cognitive dysfunction, as measured by a decrease of two or more points on the Montreal Cognitive Assessment (MoCA) scale from preoperative baseline test to the 1-year follow-up.Timepoint: 2-9 Days,30 Days, 1 year follow up
- Secondary Outcome Measures
Name Time Method Measuring the incidence of acute postoperative covert strokeTimepoint: 2-9 days,30 days and 1-year follow-up.