Sphenopalatine Ganglion Block for Treatment of Postdural Puncture Headache: A Prospective Randomized Double Blind Placebo Controlled Study
Overview
- Phase
- Not Applicable
- Intervention
- placebo
- Conditions
- Postdural Puncture Headache
- Sponsor
- Wake Forest University Health Sciences
- Locations
- 1
- Primary Endpoint
- verbal pain score
- Status
- Withdrawn
- Last Updated
- 8 years ago
Overview
Brief Summary
The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia. The investigators will be evaluating the relief of headache with those subjects receiving treatment with a sphenopalatine ganglion block with bupivacaine versus placebo, evaluating the incidence of epidural blood patch, pain score of headache at 1 hour, then 24, 48, and 72 hours lower with post study treatment versus placebo, and potential side effects of those patients receiving study therapy as well as epidural blood patch.
Investigators
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesiologists assigned class I-III
- •age \>/= 18 years
- •experiencing a postdural puncture headache within 7 days of neuraxial analgesia rated \>3/10 pain score
Exclusion Criteria
- •allergy to study medications \<18 years of age pain score on presentation \</=3/10 for headache
Arms & Interventions
placebo
sphenopalatine ganglion block performed with normal saline as the placebo
Intervention: placebo
bupivacaine
sphenopalatine ganglion block performed with bupivacaine
Intervention: bupivacaine
Outcomes
Primary Outcomes
verbal pain score
Time Frame: 1 hour
a reduction in headache verbal pain score by 3
Secondary Outcomes
- pain score(7 days)
- patient satisfaction(1 hour)
- epidural blood patch(7 days)