Blood Donor and Recipient Long-Term Outcome Study
- Conditions
- Transfusion of whole blood, erythrocyte concentrate, thrombocyte concentrate and massive transfusion (G-DRG OPS 8-800)Frozen plasma administration (OPS 8.812.6-8.812.8)Prothrombin concentrate administration (OPS 8-812.5)Fibrinogen administration (OPS 8-810.j)mechanical autotransfusion (OPS 8-803.2-3) Other blood products
- Registration Number
- DRKS00034405
- Lead Sponsor
- Goethe Universität Frankfurt, Universitätsklinikum, Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 1000000
? All individuals voluntarily donating blood, which includes the donation of red blood cells, thrombocytes, plasma, cryoplasma, and coagulation factors
? All persons who receive blood products, i.e. outpatients and inpatients who receive any quantity and type of blood products derived from human blood donors (red blood cells, platelets, plasma, cryoplasma, and coagulation factors of human origin and/or medication impacting in any way on the bone marrow (e.g. erythropoietin, iron formulations, platelet-releasing drugs, and other)
? All donors/recipients willing to give their informed consent for the study
? Any individuals that cannot give their consent can be included if someone has been granted medical power of attorney, and can consent for them
? Participants under 18 years can be included if their legal guardian(s) give(s) consent
? The coverage of the LOS Registry includes participants donating or receiving a single blood product or more and/or coagulation factors of human origin or medication impacting in any way on the bone marrow
? Registration can take place at any point in the treatment process, but must ensure that all diagnosed adverse events are recorded
none
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The registry study aims to determine any long-term effects associated with receiving and donating blood:<br><br>? First blood donation/transfusion captured by the LOS Registry<br>? Presentation of immediate adverse effects linked to blood transfusion/donation<br>? Long-term health status changes (new diagnoses, intervention, or treatment) based on annual follow-ups for 30 years since enrollment
- Secondary Outcome Measures
Name Time Method