Open Versus Laparoscopic Repair of Perforated Peptic Ulcer

Not Applicable

Recruiting

• Conditions: Perforated Peptic Ulcer
• Interventions: Procedure: laparoscopic repair of perforated peptic ulcer; Procedure: open repair of perforated peptic ulcer

• Registration Number: NCT06484699
• Lead Sponsor: Sohag University

Brief Summary

The aim of this clinical trial is to compare the outcomes of open versus laparoscopic repair for perforated peptic ulcer and provide evidence-based guidance to the selection of the most appropriate operative technique at Sohag University Hospital. The study will include patients presented with perforated peptic ulcers as a complication of peptic ulcer disease during the period of study.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-13
• Status Verified: 2024-06
• Study First Submitted: 2024-06-26
• Study First Submitted QC: 2024-06-26
• Study First Posted: 2024-07-03
• Last Update Submitted: 2025-04-30
• Last Update Posted: 2025-05-04
• Primary Completion: 2025-05-30
• Study Completion: 2025-05-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• All patients with a clinical diagnosis of perforated peptic ulcer that are fit to undergo surgery either via laparotomy or laparoscopy, males or females, any age, with gastric or duodenal ulcer, with American Society of Anesthesiologists (ASA) grade I, II, III.

Exclusion Criteria

• Patients with associated bleeding ulcer (additional steps are needed to control bleeding).
• Patients with associated pathology other than perforated peptic ulcer.
• Patients with American Society of Anesthesiologists (ASA) grade IV, V, VI.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
laparoscopic repair of perforated peptic ulcer	laparoscopic repair of perforated peptic ulcer	group (B) includes patients with perforated peptic ulcer that will be operated by laparoscopic repair approach
open repair of perforated peptic ulcer	open repair of perforated peptic ulcer	group (A) includes patients with perforated peptic ulcer that will be operated by open repair approach

Primary Outcome Measures

Name	Time	Method
Early postoperative follow up for repair of perforated peptic ulcer	3 days after the operation	resumption of oral intake

Trial Locations

Locations (1)

Sohag University Hospital; 🇪🇬 Sohag, Egypt