An adipocyte-driven mechanism for weight regain after weight loss: the yo-yo effect - ADIPOSTRESS

niversiteit Maastricht0 sites58 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

last year

Study Type

Interventional

Sponsor

•Subjects using prescription medication, or suffering from diseases or conditions that might influence the outcome of the study: this concerns diseases/medication that influence body weight regulation (malabsorption, untreated hypo/hyperthyroidism, eating disorders, systemic use of steroids, etc.) and obesity\-related cardiovascular risk factors (heart disease, systolic and diastolic blood pressures \> 160/100 mmHg, blood glucose \> 6\.1 mmol L\-1, blood cholesterol \> 7 mmol L\-1, blood triglycerides \> 3 mmol L\-1\), marked alcohol consumption \> 21 alcoholic units week\-1 (male), or \>14 alcoholic units week\-1 (female), planned major changes in physical activity during the study to an extent that might interfere with the study outcome, as judged by the investigator; blood donation within the past 2 months prior to the study; weight change of \>3 kg within 2 months prior to the study; psychiatric disease (based on medical history only); pregnant or lactating women, or women planning to become pregnant within the next 12 months; surgically treated obesity; participation in other clinical studies within the last 3 months; drug abuse (based on clinical judgment); unable to give informed consent; unable to engage in a low\-calorie diet; following a special diet (e.g. Atkins).