To compare two types of regional anaesthesia techniques i.e. erector spinae block and paravertebral block for management of pain after breast cancer surgeries

Phase 2/3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/06/053769
• Lead Sponsor: Dr JP Attri

Brief Summary

Breast cancer is one of the common malignancies among women.

Surgical resection of the primary tumor with axillary dissection is one of the main modalities of breast cancer treatment mostly done under general anaesthesia with or without regional blocks. The present study aims to compare the efficacy of ultrasound guided paravertebral block with erector spinae block for postoperative analgesia in breast cancer surgeries in Government Medical College and Hospital, Amritsar. 60 female patients of age between 20-60 years and ASA grade I and II will be randomly divided into two groups of 30 patients, each receiving erector spinae block and paravertebral block using ultrasound guidance. The procedural time, duration of sensory block, consumption of fentanyl during 24 hours, time to rescue analgesia and total dose of rescue analgesia will be assessed in both groups. Haemodynamics will be assessed. Intraoperative and postoperative complications will also be noted. The data thus obtained will be analyzed and compared statistically.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-28
• Last Update Posted: 2023-10-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Patients aged 20 –60 years American Society of Anesthesiologists (ASA) I or II Patients with normal neurological status Co-operative patients Patients undergoing breast cancer surgeries.

Exclusion Criteria

Refusal of patient for the procedure or to enlist in study Patients of American Society of Anaesthesiologists (ASA) Grade III and IV Uncooperative patients Patients with clinically significant pulmonary pathology Pregnant females Patients with coagulation disorders and on anticoagulation therapy Patient with history of allergy to local anaesthetic Known neuropathies.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Procedural time (time required to complete the block)	Baseline followed by every 30 minutes till 2 hours followed by every 2 hour till 8 hours followed by every 6 hours till 24 hours
2. Duration of sensory block	Baseline followed by every 30 minutes till 2 hours followed by every 2 hour till 8 hours followed by every 6 hours till 24 hours
3. Time to first rescue analgesia	Baseline followed by every 30 minutes till 2 hours followed by every 2 hour till 8 hours followed by every 6 hours till 24 hours
4. Total dose of rescue analgesia in 24 hours	Baseline followed by every 30 minutes till 2 hours followed by every 2 hour till 8 hours followed by every 6 hours till 24 hours

Secondary Outcome Measures

Name	Time	Method
1. Haemodynamic changes	2. Side effects and complications

Trial Locations

Locations (1)

Guru Nanak Dev Hospital Amritsar; 🇮🇳 Amritsar, PUNJAB, India

Guru Nanak Dev Hospital Amritsar

🇮🇳Amritsar, PUNJAB, India

Dr Komalpreet Kaur

Principal investigator

8699415070

kaurkharoud27@yahoo.com