NL-OMON41804已完成4 期
The effect of on demand versus continuous use of proton pump inhibitors on reflux symptoms, quality of life and self-rated health in patients with gastro-oesophageal reflux disease - Effect of on demand versus continuous use of omeprazole on reflux symptoms
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 140
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Age 18-65 years
- •* Predominant GORD cases with heartburn and/or acid regurgitation that need PPI treatment
- •* PPI responsive
- •* Ability to complete questionnaires
排除标准
- •* Known Barrett*s oesophagus
- •* Known severe oesophagitis (LA C or above)
- •* Continuous use of NSAID/aspirin
- •* Prophylactic PPI use to reduce the risk of ulcers in persons being treated with NSAIDs
- •* PPI treatment to heal an ulcer induced by NSAID treatment in the last 6 months
- •* PPI treatment for H. pylori eradication in the last 6 months
- •* Severe disorders other than GORD with a negative impact on quality of life
- •* Signs of upper gastrointestinal bleeding
- •* Alarm symptoms: unintentional weight loss/vomiting/difficulties swallowing
- •* Pregnancy
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