Research of Intracardiac Hemodynamics and Myocardial Strains of Athlete's Heart
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- intracardiac hemodynamics in mmHg/mm using vector flow mapping
研究概览
简要总结
The goal of this observational study is to compare the differences of intracardiac hemodynamics and myocardial strain in athletes with different training levels to adapt to long-term high-level training in rest conditions. The main questions aim to answer are: 1. whether an increase in amplitude and duration of intracardiac hemodynamics and myocardial strain compared with healthy controls; 2. Whether significant correlations exist between the hemodynamic indices and training level.
Participants will be asked to filling out the questionnaire, such as the age, training year (the number of years the athlete has participated in any sport), technical hierarchy (promoted by the Competitive Sports Department of the General Administration of Sport of China, weekly training time in the last 6 months, height, weight, body surface area, heart rate, systolic blood pressure, and diastolic blood pressure; and will be asked to perform an examination of transthoracic echocardiography.
Researchers will compare differences of cardiac structure and function, especially the hemodynamics and myocardial strain to see if training level could affect the cardiac function through hemodynamics and myocardial strain.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •athletes and healthy control subjects without regular exercise habits;
- •no specific medical history or chronic illness.
排除标准
- •A previous history of arterial hypertension, diabetes mellitus, heart, kidney, hepatic, infectious, psychiatric, malignant, disorders, taking drugs that can influence ECG intervals, and electrolyte imbalance;
- •poor echocardiographic image quality and abnormal segmental ventricular wall movement.
结局指标
主要结局
intracardiac hemodynamics in mmHg/mm using vector flow mapping
时间窗: through study completion, an average of 1 year
intraventricular pressure gradient from left ventricular apex to base
myocardial strain in % using two-dimension tissue tracking
时间窗: through study completion, an average of 1 year
left ventricular longitudinal strain
次要结局
- wall shear stress in pascal using vector flow mapping(through study completion, an average of 1 year)
研究者
Ping Yang
Principal Investigator
Chengdu Sport University