A biomarker study to analyze genomic variations in circulating-tumor DNA and circulating tumor cells in gastrointestinal cancers (Valor trial)

Not Applicable

Recruiting

• Conditions: Gastrointestinal cancer

• Registration Number: JPRN-UMIN000036681
• Lead Sponsor: St. Marianna University School of Medicine Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-08
• Study Completion: 2021-06-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Not provided

Exclusion Criteria

(1) Patients who are regarded as inadequate for study enrollment by investigators. (2) Patients do not agree with use of samples

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concordance in genomic profiling between ctDNA and CTC

Secondary Outcome Measures

Name	Time	Method
1. Association between genetic status in ctDNA and clinical outcomes 2. Association between genetic status in CTC and clinical outcome 3. Compare genetic change between ctDNA and CTC in mCRC patients with RAS wild-type tumors treated with anti-EGFR mAb.