Investigation of Adipose-Derived Stem Cells in Human Lipoaspirate
试验速览
- 阶段
- 不适用
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Percent of Viable ADSCs
研究概览
简要总结
The overall purpose of this study is to enhance identification and isolation of ADSCs and adipocytes, to find the optimum culturing conditions to increase growth and volume of grafts, and to study the effects of cryopreservation on ADSCs and adipocytes. Fat injections are used in aesthetic surgery but tend to disassemble over time. If the investigators can enhance growth and volume of fat in culture, the investigators could use fat grafts in reconstruction of cancer and traumatic injury defects with the patients own cultured fat cells and grafts.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adults (18-70 yrs) who have scheduled surgical lipectomy of the hips, abdomen, or thighs are prospective subjects for this study.
排除标准
- •Pregnant women will be excluded to protect the unborn child.
结局指标
主要结局
Percent of Viable ADSCs
时间窗: Day of Surgery
Percent of viable ADSCs will be measured on fresh samples and samples refrigerated for different times.
次要结局
- Percent of Apoptotic ADSCs(Day of Surgery)
研究者
William A. Zamboni, M.D.
Professor and Chair Department of Surgery UNSOM
University of Nevada, Las Vegas