Investigation the effect of cognitive and motor exercises on improving the performance of chronic stroke patients
- Conditions
- chronic stroke.Family history of stroke
- Registration Number
- IRCT20180619040156N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 3
Experience the first stroke
Passed for 6-24 months after lesion
Having ages between 35-65 years
Ability to walk at least 10 meters without auxiliary equipment
No history of falling over the past 6 months according to the patient's own report
Having an acceptable level of cognitive performance means a score of over 24 in the Mini Mental Status Examination (MMSE) test.
Not having hemi neglect using the Star Cancellation test
Not having any history of other neurological problems, orthopedics and upper limb surgeries involved according to medical records, patient's or patient's report or observation of the examiner
Having the criteria for receiving and consuming Atorvastatin drug on the basis of a neurologist's diagnosis
Central cerebral artery injury as the cause of stroke
Ability to read and write
Having understandable speech
The lack of vision problems has not been resolved
Falling during assessments and exercises
Failure to cooperate properly and correct implementation of the instructions during the tests and exercises.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Balance and upper and lower extremity mobility assessments (behavioral tests). Timepoint: Before interventions, immediately after intervention, 3 months after intervention. Method of measurement: Timed up go test, functional reach test, berg test, fugl meyer test.;Cognitive Assessments (Behavioral Tests). Timepoint: Before interventions, immediately after intervention, 3 months after intervention. Method of measurement: Wechsler test, Wisconsin test, Stroop test.;Serum levels of brain-derived growth factor (molecular laboratory tests). Timepoint: Before interventions, immediately after intervention, 3 months after intervention. Method of measurement: Brain derived neurotrophic factor analysis.;Structural changes in various brain regions (laboratory imaging test). Timepoint: Before interventions, immediately after intervention, 3 months after intervention. Method of measurement: magnetic resonance imaging.
- Secondary Outcome Measures
Name Time Method Changes in fear of falling. Timepoint: Before and after intervention and 3 months after intervention. Method of measurement: Activities-based balance confidence scale (ABC).;Quality of life score. Timepoint: Before and after intervention and 3 months after intervention. Method of measurement: Short Form (36) Health Survey (SF-36).;Changes in fatigue levels. Timepoint: Before and after intervention and 3 months after intervention. Method of measurement: Multidimensional Fatigue Symptom Inventory-Short Form.