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Clinical Survey Study to Assess Physical Function and the Incidence of Hypoglycemia in Patients 1 Year of Age and Over with GSD III.

Recruiting
Conditions
Glycogen Storage Disease III
10027424
Registration Number
NL-OMON51818
Lead Sponsor
ltragenyx pharmaceutical Inc.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
2
Inclusion Criteria

1. Male or female 1 year of age or older at time of informed consent/assent
2. Diagnosis of GSD III, confirmed by AGL sequencing or GDE enzymatic testing
3. Provide informed consent after the nature of the study has been explained,
and prior to
any research-related procedures. If a minor or an adult with cognitive
limitations, willing
and able (if possible) to provide assent and have a legally authorized
representative
provide informed consent after the nature of the study has been explained, and
prior to
any research-related procedures

Exclusion Criteria

1. Subject is unwilling to remain blinded to CGM data, or the Investigator
determines that blinding would compromise subject safety
2. Presence or history of any condition that, in the view of the Investigator,
would interfere with participation or pose undue risk
3. Use of any IP or investigational medical device within 30 days or 5.5
half-lives, whichever is longer, prior to screening, or during the study

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The primary endpoint of this study is the incidence of hypoglycemia during the<br /><br>26-week Observation Period. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Additional details regarding the primary analysis are in the Statistical<br /><br>Analysis Plan (SAP)</p><br>
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