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Clinical Trials/NCT03062293
NCT03062293
Unknown
Not Applicable

Newcastle Low Back Pain Intervention Study

Northumbria University0 sites14 target enrollmentSeptember 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Low Back Pain, Mechanical
Sponsor
Northumbria University
Enrollment
14
Primary Endpoint
Change in Intramuscular EMG of Lumbo-pelvic muscles
Last Updated
9 years ago

Overview

Brief Summary

The aim of this study is to investigate if six-weeks of exercise intervention, 3 times per week on the Functional Re-adaptive Exercise Device (FRED) reduces non-specific mechanical low back pain in adults ages 18-60.

Detailed Description

The aim of this study is to investigate whether an six-week FRED exercise intervention reduces low back pain (LBP) and improves a range of related outcomes. The objectives of this study are to examine 1. whether FRED exercise reduces mechanical LBP ( low back pain); 2. whether FRED exercise improves functional and static balance in people with LBP; 3. whether FRED exercise has an effect on cross-sectional area (CSA) of relevant lumbo-pelvic muscles; 4. whether FRED exercise has an effect on TrA (Transversus Abdominis), LM ( Lumbar Multifidus), lumbar Erector Spinae, External and Internal Oblique muscle activity and function in individuals with LBP; 5. whether FRED exercise has an effect on TrA and internal oblique muscle thickness; 6. the rate of muscle physiology change in response to FRED exercise in people with LBP; 7. whether FRED exercise affects the analgesic intake, need for intervention and physical activity level of individuals with LBP; 8. whether FRED exercise affects wellbeing and every-day function in people with LBP; 9. the rate of change of level of pain, wellbeing and of function (incl. balance) in response to FRED exercise in people with LBP.

Registry
clinicaltrials.gov
Start Date
September 2016
End Date
March 2017
Last Updated
9 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Mechanical LBP for 8 weeks or longer
  • Score of \< 15 on FABQ
  • Age 18-60
  • Commitment to taking part in the study for its full duration

Exclusion Criteria

  • Presence of "red flags" - indicative of non-mechanical LBP
  • Score of \> 15 on FABQ or other indicators of a likely poor response to a solely physical approach to treatment incl. seeking compensation for LBP
  • Exercise contraindicated as per Physical Activity Readiness Questionnaire
  • Inability to exercise safely on the FRED
  • Pregnancy
  • Surgery within the previous nine months
  • Difficulty to exercise safely in standing for 30 mins 3x/week
  • Cardio/respiratory disease
  • Neurological disorders
  • BMI \> 28 where adipose tissue infringes on ultrasound imaging and intramuscular electrode placement

Outcomes

Primary Outcomes

Change in Intramuscular EMG of Lumbo-pelvic muscles

Time Frame: within 1 week prior to intervention, and within 1 week post intervention (2 data collection

iEMG of Lumbar Multifudus (LM), Transversus Abdominus (TrA), External Obliques and Internal obliques during exercise and balance tasks

Secondary Outcomes

  • SF-36 II .(At baseline (intervention -6 weeks) within 1 week prior to intervention, within 1 week post intervention, at intervention +6 week, +12 weeks and +16 weeks follow up (5 data collections))
  • Change in muscular arcitecture via Ultrasound imaging(At baseline (intervention -6 weeks) within 1 week prior to intervention, within 1 week post intervention, 1 x week during intervention, and at intervention +12 weeks (10 data collections))
  • Participant Activity Log(Daily from baseline data collection to intervention +16 weeks follow-up (total 203 days))
  • VICON/ force plate kinematic data(within 1 week prior to intervention and and within 1 week post intervention (2 data collections))
  • Patient Specific Functional Scale(At baseline (intervention -6 weeks) within 1 week prior to intervention, within 1 week post intervention, at intervention +6 week, +12 weeks and +16 weeks follow up (5 data collections))
  • Numeric Rating Scale for Pain(At baseline (intervention -6 weeks) within 1 week prior to intervention, within 1 week post intervention, at intervention +6 week, +12 weeks and +16 weeks follow up (5 data collections))

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