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Clinical Trials/NCT06965712
NCT06965712
Recruiting
Not Applicable

Use of Point-of-Care Ultrasound (POCUS) to Guide Fluid Management and Reduce Hospital Length of Stay in Patients With Decompensated Heart Failure

Florida International University1 site in 1 country66 target enrollmentStarted: November 24, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
66
Locations
1
Primary Endpoint
Hospital Length of Stay (LOS)

Overview

Brief Summary

This study will evaluate whether using bedside ultrasound (also called Point-of-Care Ultrasound or POCUS) can help improve the care of hospitalized patients with decompensated heart failure. Patients will be randomly assigned to two groups: one group will receive ultrasound-guided assessments, and the other group will receive standard clinical evaluations. Researchers will compare the hospital length of stay between the two groups. Ultrasound is a non-invasive, safe, and painless imaging tool. The goal of the study is to find out if ultrasound guidance can lead to shorter hospitalizations and better care for patients with heart failure.

Detailed Description

This clinical trial aims to determine whether the use of bedside ultrasound (also called Point-of-Care Ultrasound, or POCUS) can improve the management of patients hospitalized with decompensated heart failure. Traditional methods for assessing heart failure patients rely heavily on physical examination and imaging tests such as chest X-rays, which may not always accurately reflect a patient's volume status. POCUS provides real-time information at the bedside, allowing clinicians to assess lung congestion and venous volume status quickly and non-invasively.

Participants in this study will be randomly assigned to one of two groups. The intervention group will undergo POCUS assessments of the lungs and inferior vena cava (IVC) twice during their hospitalization: once within 24 hours of admission and once before discharge. The control group will receive standard clinical care without ultrasound guidance. All participants' clinical information, including length of hospital stay, treatments administered, and 30-day readmission status, will be collected and analyzed.

The primary objective is to determine whether POCUS-guided management leads to a reduction in hospital length of stay. Secondary objectives include evaluating whether ultrasound guidance affects 30-day readmission rates and diuretic therapy adjustments. The study is expected to enroll approximately 66 patients.

This research may help establish whether POCUS can be incorporated into standard care practices for hospitalized heart failure patients, potentially leading to better outcomes and more efficient use of hospital resources.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Adults aged 18 years and older.
  • Hospitalized with a primary diagnosis of decompensated heart failure (left, right, or biventricular).
  • Evidence of volume overload or congestion based on Framingham criteria, clinical examination, elevated proBNP (\>1000 pg/mL), or chest X-ray showing pulmonary edema.
  • Ability to undergo bedside ultrasound evaluation (POCUS) as clinically feasible.
  • Able to provide informed consent.

Exclusion Criteria

  • Age under 18 years.
  • Pregnant or breastfeeding women.
  • Terminal illness with life expectancy \< 30 days.
  • Inability to obtain ultrasound images due to body habitus or other technical reasons.
  • Enrollment in another interventional clinical trial that could interfere with the outcomes of this study.

Arms & Interventions

POCUS-Guided Evaluation Group

Experimental

Participants in this group will receive bedside Point-of-Care Ultrasound (POCUS) evaluations of the lungs and inferior vena cava (IVC) twice during hospitalization, once within 24 hours of admission and once prior to discharge. Ultrasound findings will be used to guide fluid management decisions.

Intervention: Point-of-Care Ultrasound (POCUS) (Device)

Standard Clinical Evaluation Group

No Intervention

Participants in this group will receive standard clinical care without bedside ultrasound guidance. Clinical evaluation and management will be based on physical examination, chest X-rays, laboratory results, and physician judgment.

Outcomes

Primary Outcomes

Hospital Length of Stay (LOS)

Time Frame: From the date of hospital admission to the date of discharge order, assessed up to 30 days.

Hospital Length of Stay (LOS) will be measured as the number of days from hospital admission to discharge decision. LOS will be compared between the POCUS-guided group and the standard care group.

Secondary Outcomes

  • 30-Day Hospital Readmission Rate(Within 30 days after hospital discharge)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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