Ultrasonic Weaning Criteria in Prolonged Ventilation

Completed

• Conditions: Acute Respiratory Distress Syndrome
• Interventions: Diagnostic Test: clinical weaning criteria

• Registration Number: NCT05794867
• Lead Sponsor: King Abdul Aziz Specialist Hospital

Brief Summary

compare and evaluate the effect of use of ultrasonic criteria of weaning versus the conventional ways of weaning in post-traumatic acute respiratory distress syndrome (ARDS) patients who were ventilated for a long time. And compare their effect on the duration of ICU stay.

Detailed Description

It is a prospective double blind study done on total 200 patients. Who were weaned from ventilator after being ventilated for \> one week due to respiratory failure. This respiratory failure was selected in our study to be from severe lung contusion and post-traumatic acute respiratory distress syndrome. Patients were randomly allocated in one of two groups each group contain 100 patients. Group A considered control group. Those patients weaned from the ventilator by the conventional criteria of weaning. While group B weaned from the ventilator by the ultrasound criteria of weaning. All patients weaned from both groups followed for six days for signs of failure of weaning ,signs of post-extubation respiratory failure. And number of patients who were re-ventilated and who discharged from ICU in both groups recorded and compared.

Study Timeline

• Study Start: 2021-04-01
• Status Verified: 2023-03
• Primary Completion: 2023-03-19
• Study Completion: 2023-03-19
• Study First Submitted: 2023-03-19
• Study First Submitted QC: 2023-03-31
• Last Update Submitted: 2023-03-31
• Study First Posted: 2023-04-03
• Last Update Posted: 2023-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• adult patients between 18-65 years old,
• with Acute respiratory distress syndrome,
• any ventilated patients for more than one week

Exclusion Criteria

• young or pediatric patients below 18 years.
• patients older than 65 years
• patients had Chronic Respiratory Disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients were randomly allocated in one of two groups each group contain 100 patients.	clinical weaning criteria	Group A considered control group. Those patients weaned from the ventilator by the conventional criteria of weaning

Primary Outcome Measures

Name	Time	Method
The number of patients who had no failure of weaning	6 days	patients followed by ultrasounds criteria

Secondary Outcome Measures

Name	Time	Method
The number of patients who discharged early from ICU	6 days

Trial Locations

Locations (1)

King abd el Aziz specialist hospital; 🇸🇦 Ta'if, Saudi Arabia