Zhejiang Nutrition and Health Study: Nutrition and Lifespan Study (NuLife Study)
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 10,000
- 试验地点
- 2
- 主要终点
- Occurrence of cardio-metabolic diseases
研究概览
简要总结
This project aims to explore the relationship between healthy lifespan and nutrition through a 10-year longitudinal study in Zhejiang Province. The cohort will include individuals in a wide range of age groups. The demographic, diet, lifestyle information, health status, and corresponding bio-samples will be collected carefully. It will give a deeper insight to the relation between nutrition and healthy aging and longevity. Ultimately, this research will contribute to evidence-based nutrition interventions to improve health outcomes and enhance quality of life.
详细描述
This project aims to elucidate the relationship between healthy lifespan and nutrition through the establishment of a large-scale cohort of participants and longitudinal follow-ups spanning around 10 years in Zhejiang Province. The cohort will comprise individuals in a wide range of age groups starting at 6 years old. The participants will provide demographic information, anthropometry measurements, detailed diet, lifestyle data and health status, including 3-day dietary records and long-term food intake frequency recalls. Integrated with previous information, diverse bio-samples will also be collected to establish a multi-dimensional biobank. It will give a deeper insight to the relation between nutrition and healthy aging and longevity. Ultimately, this research will contribute to the development of evidence-based nutrition designed to improve health outcomes and enhance the quality of life for individuals of all ages.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Chinese citizens who have resided in the surveyed area for at least 6 months before the survey within the last 12 months.
- •Aged 6 years or older.
- •They are included as resident households, which are comprised of people living together in one place based on family relationships, and at least one resident with permanent household registration.
排除标准
- •Residents living in functional zones such as construction worker dormitories, military barracks, schools, nursing homes, etc.
结局指标
主要结局
Occurrence of cardio-metabolic diseases
时间窗: up to 10 years
The investigators will track for occurrence of cardio-metabolic diseases by follow-up surveys collected by the Zhejiang Center for Disease Control and Prevention.
次要结局
- Changes in fasting blood highly sensitive C-reactive protein (CRP)(Every other year， up to 10 years)
- Changes in fasting blood glucose(Every other year， up to 10 years)
- Changes in fasting blood HbA1c(Every other year， up to 10 years)
- Changes in fasting lipid metabolism(Every other year， up to 10 years)
- Changes in body mass index(Every other year， up to 10 years)
- Changes in blood pressure(Every other year， up to 10 years)
- Changes in gut microbiome profiling(Every other year， up to 10 years)