MINIMAL INVASIVE MONITORING OF VOLUME STATUS IN PATIENTS AFTER MAJOR ABDOMINAL SURGERY.

Completed

• Conditions: After major abdominal surgery; 10017998

• Registration Number: NL-OMON39163
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- Scheduled for ventilation and sedation at the PACU after elective major abdominal surgery (i.e. any type of abdominal surgery with an indication for invasive monitoring with arterial en central venous catheters)
- Aged 18-65 years.
- Being able to give written informed consent prior to surgery.

Exclusion Criteria

- Pregnancy
- Documented or suspected soybean protein and/or relevant drug allergy.
- Morbid obesity (BMI > 35)
- venous pressure (CVP) >18 mm Hg and/ or a cardiac index < 2.0 L•min-1 or dependence on high dosages of inotropic drugs after admittance to the PACU
- Severe arrhythmias
- Renal insufficiency requiring dialysis
- Intra-cardiac shunts
- Symptomatic peripheral vascular disease
- Symptomatic pulmonary disease
- Clinically significant aortic aneurysm
- Significant valvular regurgitation
- Prior diagnosis of aberrant cardiovascular anatomy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cardiac ouput measured with different pulse contour methods to measure CO<br /><br>compared to thermodilution CO measured with a PAC</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>