Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 180,402
- 试验地点
- 3
- 主要终点
- Door-to-antibiotic Time
研究概览
简要总结
Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging. The goal of this study is to determine the potential effectiveness and unintended consequences of reorganizing ED care for patients with suspected sepsis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult (age ≥18 years)
- •ED patient at Intermountain Medical Center, Utah Valley Hospital, Dixie Regional Medical Center
- •Arrival to study emergency department (ED) during study period of 11/13/2018 to 2/12/2021.
排除标准
- •(1) Trauma patient
研究组 & 干预措施
Pre-implementation usual care (intervention site)
Adult patients age ≥18 years who receive usual care after presenting to the ED of the intervention hospital emergency department before implementation of sepsis care reorganization (Code Sepsis implementation). The primary analysis will focus on the subset of patients with sepsis.
Code Sepsis post-implementation (intervention site)
Adult patients age ≥18 years presenting to the ED of the intervention hospital emergency department after implementation of sepsis care reorganization (Code Sepsis implementation). The primary analysis will focus on the subset of patients with sepsis.
干预措施: Code Sepsis protocol (full implementation) (Other)
Pre-implementation usual care (control sites)
Adult patients age ≥18 years who receive usual care after presenting to the ED of the control hospital emergency department before implementation of sepsis care reorganization (Code Sepsis implementation) at the intervention hospital. The primary analysis will focus on the subset of patients with sepsis.
Post-implementation usual care (control sites)
Adult patients age ≥18 years who receive usual care after presenting to the ED of the control hospital emergency department after implementation of sepsis care reorganization (Code Sepsis implementation) at the intervention hospital. The primary analysis will focus on the subset of patients with sepsis.
结局指标
主要结局
Door-to-antibiotic Time
时间窗: Up to 24 hours from ED arrival (an average of 3 hours)
Time from sepsis patients' emergency department arrival to intravenous (or equivalent) antibiotic initiation
次要结局
- All-cause 1-year Mortality(1 year after ED arrival)
- All-cause 30-day Mortality(30 days after ED arrival)
- Hospital Length of Stay(From the time of admission to hospital discharge (up to 1 year, average 14 days))
- Hospital Charges(From the time of admission to hospital discharge (up to 1 year, average 14 days))
- All-cause In-hospital Mortality(From the time of admission to hospital discharge (up to 1 year, average 14 days))
研究者
Ithan Peltan
Clinical Investigator
Intermountain Health Care, Inc.