Comparative study of the effect of haloperidol and dexmedetomidine on Restlessness in mechanically ventilated patients following concussion admitted to the intensive care unit of Imam Khomeini Hospital
Phase 3
- Conditions
- Delirium.Delirium due to known physiological condition
- Registration Number
- IRCT20200803048288N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
APACHE II criteria more than 48
RASS criteria between +1 to +4
At least 48 hours after hospitalization in the intensive care unit
Exclusion Criteria
Dissatisfaction of the patient's legal guardian
Patients who are candidates for surgery
Unstable hemodynamic status
History of mental illness or use of neuroleptics
History of drug use any contraindications to Dexmedetomidine or Haloperidol (Allergy, Parkinson's, Hypotension, BradyCardiac)
Renal or Hepatic Fysfunction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Delirium. Timepoint: Every 6 hours a day for 7 days. Method of measurement: APACHE II criteria.;Agitation. Timepoint: Every 6 hours a day for 7 days. Method of measurement: APACHE II criteria.
- Secondary Outcome Measures
Name Time Method Duration of hospital stay. Timepoint: Daily. Method of measurement: Total days of hospitalization after receiving the intervention.