Peripheral Nerve Blocks for Above-the-knee Amputations

Phase 4

Recruiting

• Conditions: Peripheral Vascular Diseases; Hyperglycaemia (Diabetic); Hypertension; Coronary Artery Disease; Pulmonary Disease, Chronic Obstructive

• Registration Number: NCT03404180
• Lead Sponsor: University of Florida

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-20
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Inclusion Criteria:<br><br> - Patients undergoing above-the-knee amputation or knee disarticulation<br><br> - Ability to understand and provide informed consent<br><br>Exclusion Criteria:<br><br> - Patient refusal or inability to provide informed consent<br><br> - True allergy, not sensitivity, to any of the following substances:<br><br> - <br><br> - Local anesthetics<br><br> - <br><br> - Propofol or other sedative agents<br><br> - <br><br> - General anesthetic agents<br><br> - Pregnancy<br><br> - Severe hepatic impairment<br><br> - Evidence of infection at or near the proposed needle insertion site<br><br> - Any sensorimotor deficit, whether acute or chronic, as determined by the PI<br><br> - Chronic use of opioid medication<br><br> - BMI = 35

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chi-squared tests of peripheral nerve block success as a primary anesthetic;Analysis of pain scores

Secondary Outcome Measures

Name	Time	Method
Mortality